Interactor 1: ERBB4 (Q15303)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4

Interactor 2: LRRC1 (Q9BTT6)
Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)
Gene: LRRC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 11440998
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GF_recep_IV~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms GO:0005829 - cytosol
GO:0016323 - basolateral plasma membrane
GO:0045211 - postsynaptic membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1308
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024