HitPredict

Interactor 1: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Interactor 2: CC146 (Q8IYE0)
Coiled-coil domain-containing protein 146
Gene: CCDC146

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 955
+	Hs
		1149211 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		444419 K1C19_HUMAN (48-366): 1.68e-142: 413: 56.11		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		1149398 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH2_HUMAN (91-954): 8.29e-44: 175: 12.16
+	Hs
		445085 K1C16_HUMAN (54-382): 2.63e-115: 347: 58.36		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		502919 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH3_HUMAN (6-815): 2.53e-35: 148: 11.47
+	Hs
		528413 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH8_HUMAN (2-689): 6.01e-34: 144: 11.11
+	Hs
		280880 KRT37_HUMAN (17-409): 3.47e-149: 432: 60.91		EEA1_HUMAN (13-815): 6.43e-30: 130: 11.50
+	Hs
		1149413 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH4_HUMAN (377-954): 1.64e-26: 119: 9.56
+	Hs
		522624 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH7_HUMAN (10-612): 1.77e-26: 119: 12.09
+	Hs
		724787 K1C17_HUMAN (49-367): 1.14e-116: 348: 59.88		MYH9_HUMAN (129-949): 1.25e-44: 178: 12.09
+	Hs
		213968 KRT86_HUMAN (4-416): 5.35e-96: 297: 24.82		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		281014 KRT38_HUMAN (11-413): 5.14e-89: 278: 60.89		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		522555 K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69		MYH1_HUMAN (1-382): 6.24e-13: 75.5: 7.83
+	Hs
		725143 K1C17_HUMAN (49-367): 1.14e-116: 348: 59.88		MYH10_HUMAN (293-954): 1.18e-34: 145: 10.46
+	Hs
		64599 K1C39_HUMAN (36-416): 1.51e-133: 394: 62.30		MYH7B_HUMAN (1-429): 6.82e-16: 85.1: 11.52
+	Hs
		280641 KRT34_HUMAN (1-390): 5.34e-79: 251: 89.23		CC146_HUMAN (1-955): 2.74e-59: 221: 100.00
+	Hs
		280983 KRT38_HUMAN (11-413): 5.14e-89: 278: 60.89		EEA1_HUMAN (13-815): 6.43e-30: 130: 11.50
+	Hs
		522534 K1C13_HUMAN (50-373): 2.09e-108: 328: 56.00		MYH1_HUMAN (1-382): 6.24e-13: 75.5: 7.83
+	Hs
		49550 A1A4E9_HUMAN (50-373): 1.97e-107: 326: 55.39		MYH1_HUMAN (1-382): 6.24e-13: 75.5: 7.83