HitPredict

Interactor 1: ZMY11 (Q15326)
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Gene: ZMYND11

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003690 - double-stranded DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 602 Hs			1 467
+	Hs
		950188 ZMY11_HUMAN (1-602): 0: 607: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		1078697 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1078608 KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1029463 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		170332 TIF1A_HUMAN (90-301): 1.95e-44: 172: 20.25		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		600150 TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		950328 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		1017303 BPTF_HUMAN (85-557): 3.83e-16: 84.7: 13.15		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1078607 KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		950237 KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		600125 TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		950158 BPTF_HUMAN (85-557): 3.83e-16: 84.7: 13.15		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Mm
		936623 KAT2B_MOUSE (122-254): 1.24e-31: 132: 18.52		SMAD1_MOUSE (1-467): 0: 566: 55.42
+	Hs
		171425 KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78		SMAD9_HUMAN (1-467): 0: 564: 54.56
+	Hs
		950236 KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		600151 TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Hs
		171424 KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02		SMAD9_HUMAN (1-467): 0: 564: 54.56
+	Hs
		1035634 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58
+	Xl
		1122749 TRI33_XENLA (99-255): 5.7e-41: 161: 18.78		Q9W639_XENLA (11-456): 1.34e-149: 439: 31.93
+	Hs
		167379 KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78		SMAD7_HUMAN (13-443): 2.55e-109: 331: 25.23