HitPredict

Interactor 1: ZMY11 (Q15326)
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Gene: ZMYND11

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.616

Property	Details
Experiments	16382137, 20138174
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 602 Hs			1 522
+	Hs
		1020670 ZMY11_HUMAN (1-602): 0: 607: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		129561 ZMY11_HUMAN (1-602): 0: 607: 100.00		TRAF5_HUMAN (43-500): 4.95e-87: 280: 25.23
+	Hs
		1024680 ZMY11_HUMAN (1-602): 0: 607: 100.00		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		1023665 ZMY11_HUMAN (1-602): 0: 607: 100.00		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		1030061 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1020986 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		170352 TIF1A_HUMAN (90-301): 1.95e-44: 172: 20.25		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Mm
		1141409 TIF1A_MOUSE (90-301): 6.53e-44: 170: 18.99		TRAF3_MOUSE (20-501): 4.18e-85: 275: 22.40
+	Hs
		170190 TIF1A_HUMAN (90-301): 1.95e-44: 172: 20.25		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		302048 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		1318732 TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67		TRIM4_HUMAN (61-336): 6.36e-43: 161: 12.90
+	Hs
		537129 BRPF3_HUMAN (127-549): 2.26e-38: 154: 14.13		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1029728 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		1029416 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		1030065 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRI17_HUMAN (58-408): 7.59e-43: 160: 11.86
+	Hs
		1029844 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRIM6_HUMAN (56-403): 5.03e-39: 150: 12.97
+	Hs
		1019296 TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		164401 TRI66_HUMAN (75-309): 3.16e-43: 168: 18.35		TRAF7_HUMAN (60-208): 5.13e-18: 89.5: 23.26
+	Hs
		1163031 CECR2_HUMAN (123-470): 2.1e-38: 154: 12.26		TRAF7_HUMAN (60-208): 5.13e-18: 89.5: 23.26
+	Hs
		1163053 BRPF3_HUMAN (127-549): 2.26e-38: 154: 14.13		TRAF7_HUMAN (60-208): 5.13e-18: 89.5: 23.26