HitPredict

Interactor 1: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Interactor 2: L2GL2 (Q6P1M3)
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)
Gene: LLGL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 33961781, 24366813
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LLGL~WD40
Common GO terms GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0006887 - exocytosis
and 8 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1064
Hs

1 1020
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024