HitPredict

Interactor 1: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0019901 - protein kinase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1064 Hs			1 232
+	Hs
		901162 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		894033 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852487 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		925296 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892387 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		914083 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545393 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		900495 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		951010 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436316 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915693 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120451 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		1071576 L2GL1_HUMAN (1-1064): 0: 1391: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		925363 L2GL2_HUMAN (5-979): 0: 1216: 56.97		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		925342 STXB5_HUMAN (14-1064): 0: 1055: 25.47		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		900563 STXB5_HUMAN (14-1064): 0: 1055: 25.47		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		951061 STXB5_HUMAN (14-1064): 0: 1055: 25.47		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77