HitPredict

Interactor 1: KS6A2 (Q15349)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: RPS6KA2

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 733 Hs			1 817
+	Hs
		1073494 KS6A1_HUMAN (25-733): 0: 797: 80.11		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Hs
		1073471 KS6A1_HUMAN (25-733): 0: 797: 80.11		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Mm
		1143553 KS6A2_MOUSE (1-733): 0: 830: 95.63		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		1073453 KS6A1_HUMAN (25-733): 0: 797: 80.11		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		942348 KS6A1_HUMAN (25-733): 0: 797: 80.11		DLG4_HUMAN (438-714): 5.19e-28: 122: 16.38
+	Hs
		1021498 KS6A2_HUMAN (1-733): 0: 824: 100.00		DLG1_HUMAN (435-691): 6e-19: 94.1: 15.04
+	Hs
		1049957 KS6A2_HUMAN (1-733): 0: 824: 100.00		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Hs
		883917 KS6A1_HUMAN (25-733): 0: 797: 80.11		SYJ2B_HUMAN (496-589): 9.27e-18: 82.7: 27.66
+	Hs
		850651 KS6A3_HUMAN (2-733): 0: 798: 79.13		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Hs
		1049960 KS6A1_HUMAN (25-733): 0: 797: 80.11		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Hs
		1073444 KS6A1_HUMAN (25-733): 0: 797: 80.11		MAGI2_HUMAN (254-708): 2.41e-12: 73.1: 10.48
+	Hs
		1073434 KS6A1_HUMAN (25-733): 0: 797: 80.11		MAGI3_HUMAN (223-665): 2.08e-11: 70: 11.91
+	Hs
		1073470 KS6A1_HUMAN (25-733): 0: 797: 80.11		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Dm
		113317 JIL1_DROME (16-720): 0: 572: 32.21		M9NFI9_DROME (255-816): 1.29e-53: 204: 33.63
+	Hs
		568771 KAPCA_HUMAN (402-707): 8.01e-119: 362: 29.78		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Rn
		193535 KS6B1_RAT (412-726): 2.62e-117: 364: 25.53		NEB1_RAT (1-817): 1.22e-104: 349: 46.38