HitPredict

Interactor 1: TMED2 (Q15363)
Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1)
Gene: TMED2

Interactor 2: TMED4 (Q7Z7H5)
Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3)
Gene: TMED4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EMP24_GP25L~EMP24_GP25L
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 - Golgi apparatus
GO:0006886 - intracellular protein transport
and 4 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 201
Hs

1 227
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Cg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024