HitPredict

Interactor 1: TMED2 (Q15363)
Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1)
Gene: TMED2

Interactor 2: GORS2 (Q9H8Y8)
Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59)
Gene: GORASP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11739402, 33961781, 35271311
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0007030 - Golgi organization GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 452
+	Rn
		1144348 TMED2_RAT (19-201): 1.52e-75: 227: 100.00		GORS2_RAT (1-451): 1.08e-104: 320: 88.79
+	Rn
		88733 TMED7_RAT (15-199): 1.72e-73: 223: 35.48		GORS2_RAT (1-451): 1.08e-104: 320: 88.79
+	Hs
		1333961 TMED7_HUMAN (15-199): 2.6e-73: 222: 34.95		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Rn
		1126543 TMED9_RAT (17-201): 7.25e-68: 209: 24.75		GORS2_RAT (1-451): 1.08e-104: 320: 88.79
+	Hs
		1313965 TMED9_HUMAN (1-201): 1.08e-71: 219: 24.77		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Rn
		1144353 TMEDA_RAT (15-201): 3.43e-65: 201: 21.65		GORS2_RAT (1-451): 1.08e-104: 320: 88.79
+	Hs
		1333964 TMED3_HUMAN (16-201): 2.83e-69: 212: 29.79		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Hs
		1192854 TMED4_HUMAN (14-201): 1.07e-68: 210: 22.93		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Hs
		1071819 TMED2_HUMAN (19-201): 1.52e-75: 227: 100.00		GORS1_HUMAN (1-444): 3.85e-88: 277: 37.83
+	Hs
		833340 TMEDA_HUMAN (18-201): 3.89e-63: 196: 21.47		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Hs
		1309803 TMED7_HUMAN (15-199): 2.6e-73: 222: 34.95		GORS1_HUMAN (1-444): 3.85e-88: 277: 37.83
+	Rn
		192501 TMED2_RAT (19-201): 1.52e-75: 227: 100.00		GORS1_RAT (1-451): 8.63e-86: 271: 35.95
+	Hs
		1309805 TMED3_HUMAN (16-201): 2.83e-69: 212: 29.79		GORS1_HUMAN (1-444): 3.85e-88: 277: 37.83
+	Rn
		192499 TMED9_RAT (17-201): 7.25e-68: 209: 24.75		GORS1_RAT (1-451): 8.63e-86: 271: 35.95
+	Hs
		1034808 TMED1_HUMAN (25-201): 5.42e-12: 64.3: 26.18		GORS2_HUMAN (1-452): 3.63e-100: 308: 100.00
+	Sc
		698408 EMP24_YEAST (1-201): 1.15e-56: 179: 32.85		SEC31_YEAST (181-438): 8.19e-10: 63.4: 11.07