HitPredict

Interactor 1: PCBP1 (Q15365)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3)
Gene: PCBP1

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35733260, 22105485
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 540
+	Hs
		1072122 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		1071920 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1072123 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1071975 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		1072162 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		904013 HNRPK_HUMAN (7-353): 1.94e-68: 223: 22.51		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		904093 HNRPK_HUMAN (7-353): 1.94e-68: 223: 22.51		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		1192151 FUBP2_HUMAN (237-352): 3.22e-13: 72.5: 26.72		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1056922 FUBP1_HUMAN (224-352): 2.53e-13: 72.9: 22.48		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		1056915 FUBP2_HUMAN (237-352): 3.22e-13: 72.5: 26.72		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48