HitPredict

Interactor 1: PCBP1 (Q15365)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3)
Gene: PCBP1

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26816005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 424
+	Hs
		1121936 Q53SS8_HUMAN (1-356): 2.47e-107: 320: 100.00		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1072199 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1121935 Q53SS8_HUMAN (1-356): 2.47e-107: 320: 100.00		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Hs
		1072115 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Hs
		904180 HNRPK_HUMAN (7-353): 1.94e-68: 223: 22.51		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Mm
		888826 PCBP1_MOUSE (1-356): 2.47e-107: 320: 100.00		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33
+	Hs
		128327 IF2B3_HUMAN (1-187): 4.45e-25: 107: 25.13		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Mm
		904305 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33