Interactor 1: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 32296183, 31253590, 31444342, 24981860, 17922844, 10224134, 10449727, 25416956, 23333304, 16189514, 21516116, 29401731, 30166453, 10587522, 7660129, 11739384, 35551201, 19159283, 10205047, 23988114 and 5 others

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Identification Methods two hybrid, affinity chromatography technology, pull down, fluorescent resonance energy transfer, biochemical, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Skp1_POZ~ubiquitin
Common GO terms GO:0001222 - transcription corepressor binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0016567 - protein ubiquitination
and 4 others

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Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 112
Hs

1 118
+ Mm
+ Rn
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024