HitPredict

Interactor 1: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Interactor 2: SOCS4 (Q8WXH5)
Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)
Gene: SOCS4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	23990909, 17997974, 16643902
Identification Methods	affinity chromatography technology, x-ray crystallography, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SOCS_box~Skp1_POZ
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 112 Hs			1 440
+	Hs
		256854 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		SOCS5_HUMAN (7-436): 2.94e-135: 401: 52.72
+	Hs
		1072315 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		CISH_HUMAN (212-425): 3.46e-50: 172: 22.93
+	Hs
		146630 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		SOCS2_HUMAN (234-425): 9.62e-47: 161: 25.85
+	Hs
		181868 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		SOCS1_HUMAN (260-425): 6.95e-46: 159: 22.29
+	Mm
		193346 ELOC_MOUSE (1-112): 2.74e-68: 202: 100.00		SOCS1_MOUSE (260-425): 1.6e-45: 158: 22.29
+	Mm
		193363 ELOC_MOUSE (1-112): 2.74e-68: 202: 100.00		SOCS2_MOUSE (234-425): 2.17e-45: 158: 26.34
+	Dm
		1177326 Q7JWD6_DROME (1-112): 1.74e-67: 200: 90.35		Q7JVF1_DROME (227-426): 1.35e-42: 154: 21.96
+	Hs
		147523 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		SOCS6_HUMAN (239-424): 7.84e-40: 151: 32.00
+	Mm
		193383 ELOC_MOUSE (1-112): 2.74e-68: 202: 100.00		SOCS3_MOUSE (250-422): 1.02e-38: 141: 20.09
+	Hs
		147428 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		SOCS3_HUMAN (250-422): 2.34e-37: 137: 20.09