Interactor 1: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 24438103, 28514442, 30166453, 31253590, 33961781, 11384984, 14564014, 16530799, 22479405, 17351129, 15574593, 21145461, 23098073, 23806657, 24076655, 24390335, 24390320, 24402281, 32513959, 35551201 and 2 others

more...

Identification Methods pull down, affinity chromatography technology, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0030674 - protein-macromolecule adaptor activity
GO:0031466 - Cul5-RING ubiquitin ligase complex
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 112
Hs

1 780
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm

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Last updated: 15 Jul 2024