HitPredict

Interactor 1: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Interactor 2: ASB8 (Q9H765)
Ankyrin repeat and SOCS box protein 8 (ASB-8)
Gene: ASB8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	19159283, 12559969, 33961781, 21988832, 24337577
Identification Methods	two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	SOCS_box~Skp1_POZ
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 112 Hs			1 288
+	Hs
		1072342 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB1_HUMAN (21-286): 2.31e-54: 181: 26.89
+	Hs
		1072307 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB7_HUMAN (20-287): 4.21e-54: 180: 24.19
+	Hs
		1072263 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB13_HUMAN (13-154): 3.46e-36: 132: 34.97
+	Hs
		1072258 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB11_HUMAN (1-170): 3.77e-27: 109: 23.43
+	Hs
		1072279 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB9_HUMAN (19-155): 8.99e-25: 102: 28.26
+	Hs
		1072257 ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00		ASB5_HUMAN (7-111): 2.31e-11: 65.2: 26.67