HitPredict

Interactor 1: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	31253590, 19940151, 23401859, 18323857, 12050673, 12004076, 17353276
Identification Methods	affinity chromatography technology, surface plasmon resonance, filter binding, enzyme linked immunosorbent assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 826
+	Hs
		1072435 ELOB_HUMAN (1-118): 1.64e-66: 198: 100.00		EPAS1_HUMAN (4-824): 5.7e-171: 518: 41.24
+	Hs
		649115 ELOB_HUMAN (1-118): 1.64e-66: 198: 100.00		ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06