Interactor 1: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB
Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25499913, 24438103, 30166453, 31253590, 11384984, 14564014, 16530799, 22479405, 17351129, 15574593, 21145461, 23098073, 23806657, 24076655, 24390335, 24390320, 24402281, 21119685, 20463065 |
| Identification Methods | affinity chromatography technology, pull down, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~ubiquitin, Cullin_Nedd8~ubiquitin |
| Common GO terms | GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0031466 - Cul5-RING ubiquitin ligase complex GO:0031625 - ubiquitin protein ligase binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
