HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29121065
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 998 Hs			1 690
+	Hs
		1072558 EPHA7_HUMAN (1-998): 0: 1310: 100.00		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Hs
		872678 EPHA4_HUMAN (4-998): 0: 1224: 62.29		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Hs
		665633 EPHB2_HUMAN (32-997): 0: 1178: 57.48		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Hs
		872410 EPHB3_HUMAN (29-996): 0: 1113: 55.52		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Hs
		1021499 EPHA7_HUMAN (1-998): 0: 1310: 100.00		DLG1_HUMAN (314-690): 1.08e-30: 130: 16.15
+	Hs
		1020163 EPHA7_HUMAN (1-998): 0: 1310: 100.00		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		1072560 EPHA7_HUMAN (1-998): 0: 1310: 100.00		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		1049958 EPHA7_HUMAN (1-998): 0: 1310: 100.00		SCRIB_HUMAN (215-592): 4.05e-12: 72: 11.68
+	Hs
		872639 EPHA4_HUMAN (4-998): 0: 1224: 62.29		DLG1_HUMAN (314-690): 1.08e-30: 130: 16.15
+	Hs
		872433 EPHA5_HUMAN (6-988): 0: 1197: 62.65		DLG1_HUMAN (314-690): 1.08e-30: 130: 16.15
+	Hs
		872638 EPHA4_HUMAN (4-998): 0: 1224: 62.29		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		872679 EPHA4_HUMAN (4-998): 0: 1224: 62.29		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		872431 EPHA5_HUMAN (6-988): 0: 1197: 62.65		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		665393 EPHA3_HUMAN (25-990): 0: 1189: 62.01		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		665589 EPHB2_HUMAN (32-997): 0: 1178: 57.48		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		872464 EPHA5_HUMAN (6-988): 0: 1197: 62.65		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		665414 EPHA3_HUMAN (25-990): 0: 1189: 62.01		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		665600 EPHB2_HUMAN (32-997): 0: 1178: 57.48		SCRIB_HUMAN (215-592): 4.05e-12: 72: 11.68
+	Hs
		665228 EPHA2_HUMAN (29-989): 0: 1080: 50.42		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		665294 EPHA2_HUMAN (29-989): 0: 1080: 50.42		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13