HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3, PK_Tyr_Ser-Thr~Pkinase, Pkinase~SAM_1
Common GO terms	GO:0005524 - ATP binding GO:0007420 - brain development GO:0022407 - regulation of cell-cell adhesion GO:0030425 - dendrite
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 1332
+	Hs
		872460 EPHA5_HUMAN (6-988): 0: 1197: 62.65		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Hs
		1072625 EPHA7_HUMAN (1-998): 0: 1310: 100.00		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		324809 EPHA7_HUMAN (1-998): 0: 1310: 100.00		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		872502 EPHA5_HUMAN (6-988): 0: 1197: 62.65		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		665680 EPHB2_HUMAN (32-997): 0: 1178: 57.48		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		324762 EPHA4_HUMAN (4-998): 0: 1224: 62.29		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324761 EPHA5_HUMAN (6-988): 0: 1197: 62.65		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324742 EPHB2_HUMAN (32-997): 0: 1178: 57.48		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324738 EPHA1_HUMAN (10-986): 0: 975: 44.30		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		1072635 EPHA7_HUMAN (1-998): 0: 1310: 100.00		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60
+	Hs
		872510 EPHA5_HUMAN (6-988): 0: 1197: 62.65		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60
+	Hs
		411417 INSR_HUMAN (284-953): 2.01e-145: 470: 24.71		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		674399 UFO_HUMAN (271-950): 5.35e-149: 467: 22.78		M3K10_HUMAN (21-845): 1.48e-113: 381: 19.26
+	Hs
		987310 TYRO3_HUMAN (275-905): 4.37e-145: 456: 23.65		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60
+	Hs
		412163 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99
+	Hs
		442897 HCK_HUMAN (611-891): 2.73e-64: 228: 42.40		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60
+	Hs
		412425 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60