HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: LRIQ1 (Q96JM4)
Leucine-rich repeat and IQ domain-containing protein 1
Gene: LRRIQ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 1722
+	Hs
		665419 EPHA3_HUMAN (25-990): 0: 1189: 62.01		LRIQ1_HUMAN (1-1722): 0: 1015: 100.00
+	Hs
		665646 EPHB2_HUMAN (32-997): 0: 1178: 57.48		LRIQ1_HUMAN (1-1722): 0: 1015: 100.00
+	Hs
		665312 EPHA2_HUMAN (29-989): 0: 1080: 50.42		LRIQ1_HUMAN (1-1722): 0: 1015: 100.00
+	Hs
		872564 EPHB4_HUMAN (18-989): 0: 1023: 48.58		LRIQ1_HUMAN (1-1722): 0: 1015: 100.00
+	Hs
		665407 EPHA3_HUMAN (25-990): 0: 1189: 62.01		LRC49_HUMAN (943-1152): 3.03e-15: 83.3: 25.00
+	Hs
		412308 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		LRIQ1_HUMAN (1-1722): 0: 1015: 100.00
+	Hs
		665495 EPHA8_HUMAN (32-998): 0: 1119: 57.23		LRC49_HUMAN (943-1152): 3.03e-15: 83.3: 25.00
+	Hs
		872546 EPHB4_HUMAN (18-989): 0: 1023: 48.58		LRC33_HUMAN (812-1118): 6.58e-33: 140: 16.29
+	At
		83707 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57
+	At
		83721 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		Y3804_ARATH (756-1313): 2.03e-69: 256: 16.92
+	At
		83725 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		MIK1_ARATH (811-1160): 6.37e-55: 212: 14.62
+	At
		83702 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		RGI3_ARATH (1049-1533): 1.31e-35: 150: 14.72
+	Hs
		551614 UFO_HUMAN (271-950): 5.35e-149: 467: 22.78		DESP_HUMAN (11-715): 2.52e-22: 107: 13.21
+	Hs
		537756 INSRR_HUMAN (290-929): 3.09e-151: 484: 25.27		LRC49_HUMAN (943-1152): 3.03e-15: 83.3: 25.00
+	At
		83704 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		Y4361_ARATH (1107-1336): 7.9e-21: 102: 11.48
+	Hs
		411426 INSR_HUMAN (284-953): 2.01e-145: 470: 24.71		LRC49_HUMAN (943-1152): 3.03e-15: 83.3: 25.00
+	Hs
		674530 UFO_HUMAN (271-950): 5.35e-149: 467: 22.78		LRC40_HUMAN (816-1119): 1.32e-12: 74.8: 25.80
+	At
		83724 Y5182_ARATH (320-929): 4.26e-146: 459: 16.00		PXC2_ARATH (1196-1410): 3.18e-09: 64.1: 9.82
+	Hs
		411983 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		DESP_HUMAN (11-715): 2.52e-22: 107: 13.21