HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 1116
+	Hs
		872491 EPHA5_HUMAN (6-988): 0: 1197: 62.65		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		665661 EPHB2_HUMAN (32-997): 0: 1178: 57.48		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		600673 EPHA1_HUMAN (10-986): 0: 975: 44.30		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		171334 EPHB6_HUMAN (32-996): 0: 927: 40.44		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		1072603 EPHA7_HUMAN (1-998): 0: 1310: 100.00		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		872669 EPHA4_HUMAN (4-998): 0: 1224: 62.29		MAGI2_HUMAN (4-650): 6.29e-50: 195: 11.18
+	Hs
		872712 EPHA4_HUMAN (4-998): 0: 1224: 62.29		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		872492 EPHA5_HUMAN (6-988): 0: 1197: 62.65		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		665662 EPHB2_HUMAN (32-997): 0: 1178: 57.48		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		600712 EPHA1_HUMAN (10-986): 0: 975: 44.30		PKHA6_HUMAN (109-1116): 8.74e-73: 264: 28.52
+	Hs
		665271 EPHA2_HUMAN (29-989): 0: 1080: 50.42		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		171335 EPHB6_HUMAN (32-996): 0: 927: 40.44		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		600632 EPHA1_HUMAN (10-986): 0: 975: 44.30		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		411498 INSR_HUMAN (284-953): 2.01e-145: 470: 24.71		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		674531 UFO_HUMAN (271-950): 5.35e-149: 467: 22.78		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		674522 UFO_HUMAN (271-950): 5.35e-149: 467: 22.78		WWP1_HUMAN (3-240): 7.83e-24: 110: 14.94
+	Hs
		412353 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		412307 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93