HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: AGAP1 (Q9UPQ3)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)
Gene: AGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~fn3, Ras~fn3
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 857
+	Hs
		91534 EPHA7_HUMAN (1-998): 0: 1310: 100.00		E7EUN2_HUMAN (26-857): 0: 722: 86.54
+	Hs
		665688 EPHB2_HUMAN (32-997): 0: 1178: 57.48		GIT1_HUMAN (616-848): 2.84e-73: 257: 31.58
+	Hs
		665371 EPHA2_HUMAN (29-989): 0: 1080: 50.42		GIT1_HUMAN (616-848): 2.84e-73: 257: 31.58
+	Hs
		411483 INSR_HUMAN (284-953): 2.01e-145: 470: 24.71		AGAP2_HUMAN (52-827): 0: 597: 52.94
+	Mm
		546273 INSR_MOUSE (287-953): 6e-144: 465: 24.56		AGAP2_MOUSE (53-827): 0: 579: 52.95
+	Hs
		987307 TYRO3_HUMAN (275-905): 4.37e-145: 456: 23.65		ASAP1_HUMAN (367-855): 1.34e-86: 300: 20.87
+	Hs
		195776 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		ASAP2_HUMAN (367-855): 2.92e-95: 322: 19.77
+	Hs
		442894 HCK_HUMAN (611-891): 2.73e-64: 228: 42.40		ASAP1_HUMAN (367-855): 1.34e-86: 300: 20.87
+	Hs
		412404 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		ASAP1_HUMAN (367-855): 1.34e-86: 300: 20.87
+	Hs
		412284 FYN_HUMAN (627-891): 1.29e-62: 224: 43.45		ARAP2_HUMAN (556-846): 2.29e-75: 271: 27.70