Interactor 1: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.713

The method score is based on:

Property Details
Experiments 15854902, 33157014, 24337580, 15878852, 17470430
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0030295 - protein kinase activator activity
GO:0031669 - cellular response to nutrient levels
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 184
Hs

1 1335
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024