HitPredict

Interactor 1: UBE3C (Q15386)
Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL)
Gene: UBE3C

Interactor 2: UBE3C (Q15386)
Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL)
Gene: UBE3C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 11278995, 26949039, 28425671, 30503554, 33853758, 9575161, 22496338
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HECT~HECT
Common GO terms GO:0000209 - protein polyubiquitination
GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0035519 - protein K29-linked ubiquitination
GO:0061630 - ubiquitin protein ligase activity
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1083
Hs

1 1083
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024