HitPredict

Interactor 1: UBE3C (Q15386)
Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL)
Gene: UBE3C

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27320910
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1083 Hs			1 826
+	Hs
		1085687 SMUF2_HUMAN (557-1080): 7.6e-179: 542: 22.77		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		126123 UBE3A_HUMAN (384-1082): 0: 557: 21.73		BMAL1_HUMAN (7-505): 9.03e-114: 361: 20.88
+	Hs
		983198 UBE3A_HUMAN (384-1082): 0: 557: 21.73		BMAL2_HUMAN (2-508): 4.15e-112: 357: 21.27
+	Hs
		983285 UBE3A_HUMAN (384-1082): 0: 557: 21.73		NCOA3_HUMAN (1-746): 4.42e-98: 335: 15.31
+	Hs
		126144 HUWE1_HUMAN (683-1083): 1.53e-47: 188: 32.60		BMAL1_HUMAN (7-505): 9.03e-114: 361: 20.88