Interactor 1: SF3B3 (Q15393)
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
Gene: SF3B3

Interactor 2: PHF5A (Q7RTV0)
PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b)
Gene: PHF5A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 24981860, 37071682, 27720643, 33961781, 35235311
Identification Methods affinity chromatography technology, cross-linking study, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~PHF5, MMS1_N~PHF5
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0005684 - U2-type spliceosomal complex
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1217
Hs

1 110
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024