HitPredict

Interactor 1: SF3B3 (Q15393)
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
Gene: SF3B3

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	21182203, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1217 Hs			1 530
+	Hs
		487458 SF3B3_HUMAN (1-1217): 0: 1474: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1082307 DDB1_HUMAN (2-1211): 0: 1062: 21.10		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369692 DDB1_HUMAN (2-1211): 0: 1062: 21.10		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1014175 CPSF1_HUMAN (701-1216): 4.42e-121: 410: 15.99		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		487376 CPSF1_HUMAN (701-1216): 4.42e-121: 410: 15.99		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59