Interactor 1: TLR1 (Q15399)
Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281)
Gene: TLR1

Interactor 2: TLR1 (Q15399)
Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281)
Gene: TLR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.42 1.00 0.653

The method score is based on:

Property Details
Experiments 23155421
Identification Methods tox-r dimerization assay, fluorescence technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, LRR_8~LRRCT, TIR~TIR
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
and 19 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 786
Hs

1 786
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024