Interactor 1: TLR1 (Q15399)
Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281)
Gene: TLR1

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 28514442
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007165 - signal transduction
GO:0032755 - positive regulation of interleukin-6 production
GO:0032757 - positive regulation of interleukin-8 production
GO:0032760 - positive regulation of tumor necrosis factor production
GO:0045087 - innate immune response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 786
Hs

1 540
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024