Interactor 1: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3
Interactor 2: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12213830 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ins145_P3_rec~Ins145_P3_rec, Ins145_P3_rec~MIR, Ins145_P3_rec~RIH_assoc, Ins145_P3_rec~RYDR_ITPR, EF-hand_7~Ion_trans, Ion_trans~Ion_trans, Ion_trans~RR_TM4-6, MIR~MIR, MIR~RYDR_ITPR, RR_TM4-6~RR_TM4-6, RYDR_ITPR~RYDR_ITPR, RYDR_ITPR~SPRY, RyR~RyR, RyR~SPRY, SPRY~SPRY |
Common GO terms | GO:0005219 - ryanodine-sensitive calcium-release channel activity GO:0005509 - calcium ion binding GO:0005516 - calmodulin binding GO:0005790 - smooth endoplasmic reticulum GO:0006816 - calcium ion transport and 12 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024