Interactor 1: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3

Interactor 2: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12213830
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ins145_P3_rec~Ins145_P3_rec, Ins145_P3_rec~MIR, Ins145_P3_rec~RIH_assoc, Ins145_P3_rec~RYDR_ITPR, EF-hand_7~Ion_trans, Ion_trans~Ion_trans, Ion_trans~RR_TM4-6, MIR~MIR, MIR~RYDR_ITPR, RR_TM4-6~RR_TM4-6, RYDR_ITPR~RYDR_ITPR, RYDR_ITPR~SPRY, RyR~RyR, RyR~SPRY, SPRY~SPRY
Common GO terms GO:0005219 - ryanodine-sensitive calcium-release channel activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005790 - smooth endoplasmic reticulum
GO:0006816 - calcium ion transport
and 12 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 4870
Hs

1 4967
+ Oc
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024