HitPredict

Interactor 1: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Interactor 2: NHRF3 (Q5T2W1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3)
Gene: PDZK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.50	0.373

Property	Details
Experiments	30726710
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 735 Hs			1 519
+	Hs
		942348 KS6A1_HUMAN (1-735): 0: 836: 100.00		DLG4_HUMAN (3-344): 2.27e-36: 145: 17.22
+	Hs
		1073470 KS6A1_HUMAN (1-735): 0: 836: 100.00		MAGI1_HUMAN (183-460): 1.21e-20: 98.3: 19.89
+	Hs
		1073453 KS6A1_HUMAN (1-735): 0: 836: 100.00		LNX1_HUMAN (4-213): 1.57e-20: 97.1: 16.74
+	Hs
		1049960 KS6A1_HUMAN (1-735): 0: 836: 100.00		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		1073423 KS6A1_HUMAN (1-735): 0: 836: 100.00		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17
+	Hs
		1073444 KS6A1_HUMAN (1-735): 0: 836: 100.00		MAGI2_HUMAN (76-502): 3.32e-13: 74.8: 12.13
+	Hs
		1073434 KS6A1_HUMAN (1-735): 0: 836: 100.00		MAGI3_HUMAN (174-503): 8.59e-11: 67.1: 13.01
+	Hs
		153900 KS6A3_HUMAN (1-735): 0: 791: 79.14		NHRF1_HUMAN (5-134): 6.99e-24: 104: 31.54
+	Hs
		850651 KS6A3_HUMAN (1-735): 0: 791: 79.14		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		850657 KS6A3_HUMAN (1-735): 0: 791: 79.14		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17
+	Hs
		681891 AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92		NHRF3_HUMAN (1-519): 1.87e-114: 350: 100.00
+	Mm
		933108 KAPCB_MOUSE (416-712): 7.52e-113: 346: 29.90		DLG4_MOUSE (3-344): 3.77e-36: 144: 16.96
+	Hs
		153882 AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92		NHRF1_HUMAN (5-134): 6.99e-24: 104: 31.54
+	Mm
		1143553 KS6A2_MOUSE (2-331): 2.44e-102: 332: 23.68		DLG4_MOUSE (3-344): 3.77e-36: 144: 16.96
+	Hs
		647882 MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48		PTN13_HUMAN (72-497): 1.88e-29: 125: 12.84
+	Hs
		1049957 KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		1021498 KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80		DLG1_HUMAN (289-461): 1.6e-16: 85.1: 18.52
+	Hs
		117007 SGK1_HUMAN (415-667): 1.07e-29: 124: 33.85		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17