HitPredict

Interactor 1: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	30726710
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 735 Hs			1 728
+	Hs
		942348 KS6A1_HUMAN (1-735): 0: 836: 100.00		DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22
+	Hs
		1073444 KS6A1_HUMAN (1-735): 0: 836: 100.00		MAGI2_HUMAN (151-509): 8.26e-19: 93.6: 11.36
+	Hs
		1073434 KS6A1_HUMAN (1-735): 0: 836: 100.00		MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75
+	Hs
		1049960 KS6A1_HUMAN (1-735): 0: 836: 100.00		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		1073438 KS6A1_HUMAN (1-735): 0: 836: 100.00		PZRN4_HUMAN (258-373): 1.54e-13: 76.6: 20.51
+	Hs
		1073454 KS6A1_HUMAN (1-735): 0: 836: 100.00		PAR3L_HUMAN (465-724): 7.39e-13: 74.3: 27.90
+	Hs
		1073433 KS6A1_HUMAN (1-735): 0: 836: 100.00		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		1073495 KS6A1_HUMAN (1-735): 0: 836: 100.00		PZRN3_HUMAN (193-398): 3.72e-11: 68.9: 15.24
+	Hs
		850651 KS6A3_HUMAN (1-735): 0: 791: 79.14		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		568742 KAPCA_HUMAN (414-712): 3.66e-114: 350: 29.71		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		647930 MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		647882 MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Hs
		1021498 KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Mm
		933108 KAPCB_MOUSE (416-712): 7.52e-113: 346: 29.90		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		681891 AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Mm
		1143553 KS6A2_MOUSE (2-331): 2.44e-102: 332: 23.68		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		1049957 KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52