HitPredict

Interactor 1: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 424 Hs			1 523
+	Hs
		1031404 PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516511 HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613467 SF3B4_HUMAN (1-424): 5.15e-61: 205: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		516471 TIAR_HUMAN (2-243): 1.86e-47: 168: 20.74		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516495 PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1069687 ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Dm
		1098064 Q24534_DROME (1-220): 4.32e-92: 283: 79.50		Q9VYI0_DROME (10-157): 7.3e-15: 78: 24.52
+	Hs
		613470 ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1073633 SF3B4_HUMAN (1-424): 5.15e-61: 205: 100.00		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		474021 PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		1048074 HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		680465 TIA1_HUMAN (8-386): 4.48e-53: 183: 24.43		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35
+	Hs
		680455 TIA1_HUMAN (8-386): 4.48e-53: 183: 24.43		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1048209 HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		963526 TIAR_HUMAN (2-243): 1.86e-47: 168: 20.74		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1020249 PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1031344 PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1020265 ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1077376 ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11