Interactor 1: SC23A (Q15436)
Protein transport protein Sec23A (hSec23A) (SEC23-related protein A)
Gene: SEC23A

Interactor 2: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0005096 - GTPase activator activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0008270 - zinc ion binding
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 765
Hs

1 767
+ Hs
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+ Hs
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+ Ce
+ Ce
+ Sp
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+ Sc
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+ Sp

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Last updated: 15 Jul 2024