HitPredict

Interactor 1: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Interactor 2: SAR1A (Q9NR31)
Small COPII coat GTPase SAR1A (EC 3.6.5.2) (COPII-associated small GTPase) (Secretion-associated Ras-related GTPase 1A)
Gene: SAR1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30596474, 35844135
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~Gelsolin, Arf~Sec23_helical, Arf~Sec23_trunk, Arf~zf-Sec23_Sec24
Common GO terms	GO:0006886 - intracellular protein transport GO:0030127 - COPII vesicle coat GO:0070971 - endoplasmic reticulum exit site GO:0090110 - COPII-coated vesicle cargo loading
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 767 Hs			1 198
+	Hs
		1074099 SC23B_HUMAN (1-767): 0: 1075: 100.00		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		1074010 SC23A_HUMAN (1-766): 0: 1050: 84.73		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		1074033 SC23A_HUMAN (1-766): 0: 1050: 84.73		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Sc
		546683 SEC23_YEAST (9-764): 0: 860: 49.94		SAR1_YEAST (4-197): 2.97e-75: 226: 59.79
+	Hs
		315772 SC24B_HUMAN (6-754): 0: 591: 18.75		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		315789 SC24B_HUMAN (6-754): 0: 591: 18.75		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		867133 SC24C_HUMAN (2-721): 0: 570: 16.67		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		315598 SC24A_HUMAN (4-760): 0: 559: 19.20		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		297878 SC24D_HUMAN (9-680): 0: 557: 16.78		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		867145 SC24C_HUMAN (2-721): 0: 570: 16.67		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		315614 SC24A_HUMAN (4-760): 0: 559: 19.20		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		297879 SC24D_HUMAN (9-680): 0: 557: 16.78		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Sc
		594407 SEC24_YEAST (10-663): 1.02e-168: 511: 15.04		SAR1_YEAST (4-197): 2.97e-75: 226: 59.79