HitPredict

Interactor 1: SF3A1 (Q15459)
Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)
Gene: SF3A1

Interactor 2: SF01 (Q15637)
Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)
Gene: SF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	22365833, 26420826
Identification Methods	two hybrid, anti bait coimmunoprecipitation, two hybrid fragment pooling approach, anti tag coimmunoprecipitation, pull down
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000389 - mRNA 3'-splice site recognition GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005681 - spliceosomal complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 639
+	Hs
		1075707 TITIN_HUMAN (293-702): 3.81e-38: 156: 16.70		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Sc
		692439 PRP21_YEAST (48-340): 6.51e-49: 176: 20.68		BBP_YEAST (20-472): 1.32e-49: 181: 32.75
+	Ce
		105294 G5ECL3_CAEEL (609-793): 3.72e-19: 94.2: 29.73		Q20763_CAEEL (70-280): 7.86e-37: 140: 21.24
+	Dm
		113976 M9PB30_DROME (433-757): 1.67e-12: 73.7: 12.57		M9PB30_DROME (223-638): 9.47e-20: 96.7: 15.03
+	Mm
		1351630 PCLO_MOUSE (213-769): 1.78e-09: 63.9: 11.13		PCLO_MOUSE (294-637): 6.46e-11: 68.1: 16.16