HitPredict

Interactor 1: SF3A1 (Q15459)
Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)
Gene: SF3A1

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 24981860, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0045292 - mRNA cis splicing, via spliceosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 401
+	Hs
		1054338 SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641797 SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1074257 SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		212144 SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00		HTSF1_HUMAN (305-388): 4.02e-17: 85.4: 27.78
+	Hs
		924300 RL40_HUMAN (722-790): 6.93e-24: 99.4: 30.44		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1264818 TITIN_HUMAN (293-702): 3.81e-38: 156: 16.70		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		1335172 CDHR5_HUMAN (444-689): 2.47e-41: 164: 16.93		MAN1_HUMAN (292-395): 2.1e-27: 116: 16.96
+	Hs
		554269 MUC1_HUMAN (253-757): 1.26e-24: 112: 9.32		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93