HitPredict

Interactor 1: SKI2 (Q15477)
Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP)
Gene: SKIC2

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1246 Hs			1 523
+	Sc
		376837 MTR4_YEAST (168-1244): 0: 687: 32.26		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Sp
		143097 YE02_SCHPO (190-1244): 0: 625: 30.72		PABP_SCHPO (2-149): 1.81e-23: 106: 15.39
+	Hs
		1263553 DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1263493 DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		134137 DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516711 DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		133858 DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613538 DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1232181 ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516589 ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		134018 DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1232194 ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1077513 DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1314627 DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		1077436 DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Sc
		376698 BRR2_YEAST (251-1053): 3.74e-53: 207: 15.65		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1271643 DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Sp
		678721 BRR2_SCHPO (208-1101): 4.77e-72: 267: 15.38		PABP_SCHPO (2-149): 1.81e-23: 106: 15.39
+	Hs
		1232198 ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04