HitPredict

Interactor 1: G5EFC1 (G5EFC1)
Rab8 (Ras-related protein Rab-8A)
Gene: rab-8

Interactor 2: Q23419 (Q23419)
PH domain-containing protein
Gene: tbc-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	23100538
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Ras, RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Ce			1 908
+	Ce
		1095338 RAB10_CAEEL (3-173): 6.4e-88: 259: 71.35		Q23419_CAEEL (1-908): 0: 681: 100.00
+	Hs
		914465 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		TBD2B_HUMAN (16-902): 6.3e-162: 500: 26.29
+	Hs
		232698 RAB2B_HUMAN (4-208): 2.32e-95: 278: 44.86		TBCD4_HUMAN (104-906): 9.22e-107: 360: 15.74
+	Hs
		894747 RAB8A_HUMAN (1-204): 4.67e-83: 247: 72.06		TBC9B_HUMAN (200-905): 1.46e-103: 351: 17.76
+	Hs
		894778 RAB8A_HUMAN (1-204): 4.67e-83: 247: 72.06		TBC15_HUMAN (319-905): 6.87e-94: 313: 12.80
+	Hs
		914423 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		TBC14_HUMAN (346-907): 1.57e-90: 303: 15.02
+	Dd
		595732 RAB8A_DICDI (2-203): 2.36e-94: 275: 63.37		Q54IZ7_DICDI (586-904): 2.08e-78: 272: 24.77
+	Hs
		914176 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		TBCD1_HUMAN (432-907): 1.71e-82: 291: 18.43
+	Os
		1130875 Q84TA8_ORYSJ (4-206): 2.1e-88: 260: 59.80		Q5SMT0_ORYSJ (512-881): 5.22e-79: 272: 17.83
+	Os
		1130874 Q7XHP7_ORYSJ (4-206): 2.14e-87: 258: 60.49		Q5SMT0_ORYSJ (512-881): 5.22e-79: 272: 17.83
+	Hs
		918951 RAB1A_HUMAN (1-207): 9.61e-85: 251: 52.17		TBC17_HUMAN (364-886): 1.16e-81: 278: 13.68
+	Hs
		914367 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		PKHA5_HUMAN (17-630): 1.27e-79: 282: 10.56
+	Hs
		894809 RAB8A_HUMAN (1-204): 4.67e-83: 247: 72.06		TBC17_HUMAN (364-886): 1.16e-81: 278: 13.68
+	Hs
		894727 RAB8A_HUMAN (1-204): 4.67e-83: 247: 72.06		TBC8B_HUMAN (241-906): 1.77e-77: 276: 16.94
+	Hs
		321281 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		TBCD8_HUMAN (561-905): 8.15e-78: 277: 25.28
+	Hs
		233036 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		TBC12_HUMAN (465-906): 4.52e-79: 274: 16.81
+	Hs
		234370 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		EVI5_HUMAN (594-892): 1.23e-78: 274: 26.16
+	Os
		772871 RIC2_ORYSJ (4-209): 1.33e-82: 246: 38.65		Q5SMT0_ORYSJ (512-881): 5.22e-79: 272: 17.83
+	Hs
		895536 RAB10_HUMAN (3-185): 6.14e-91: 266: 69.47		EVI5L_HUMAN (623-850): 5.58e-21: 100: 28.95
+	Hs
		914275 RB11A_HUMAN (4-208): 2.44e-82: 245: 43.00		EVI5L_HUMAN (623-850): 5.58e-21: 100: 28.95