HitPredict

Interactor 1: SSXT (Q15532)
Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)
Gene: SS18

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24981860, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003713 - transcription coactivator activity GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II GO:0016514 - SWI/SNF complex and 1 others more... GO:0071564 - npBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 1214
+	Hs
		1074759 SSXT_HUMAN (1-418): 1.23e-79: 253: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		60093 A4PIV7_HUMAN (1-410): 6.25e-75: 243: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		257495 CREST_HUMAN (1-418): 2.69e-58: 197: 55.26		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		257509 CREST_HUMAN (1-418): 2.69e-58: 197: 55.26		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1251642 S18L2_HUMAN (1-73): 2.45e-38: 134: 52.06		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		846825 SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1272958 S18L2_HUMAN (1-73): 2.45e-38: 134: 52.06		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		847025 SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		846839 SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		847045 SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Mm
		1111940 SMCA4_MOUSE (70-418): 2.39e-19: 92.8: 16.11		SMRC2_MOUSE (1-1203): 0: 957: 96.51
+	Mm
		956808 SMCA4_MOUSE (70-418): 2.39e-19: 92.8: 16.11		SMRC1_MOUSE (4-1028): 0: 952: 64.13
+	Hs
		159804 CREST_HUMAN (1-418): 2.69e-58: 197: 55.26		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		3232 CREST_HUMAN (1-418): 2.69e-58: 197: 55.26		A0A0S2Z4Q4_HUMAN (748-1181): 4.67e-43: 170: 19.11
+	Mm
		1111936 SMCA4_MOUSE (70-418): 2.39e-19: 92.8: 16.11		MYSM1_MOUSE (276-523): 3.33e-50: 194: 19.16
+	Hs
		232058 SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		261443 SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Mm
		57185 SMCA4_MOUSE (70-418): 2.39e-19: 92.8: 16.11		CHD7_MOUSE (856-1214): 3.35e-12: 73.5: 11.26
+	Hs
		297843 SC24D_HUMAN (132-403): 1.54e-19: 93.2: 18.12		SC31A_HUMAN (741-1068): 3.97e-10: 66.6: 9.06
+	Hs
		302269 SC24C_HUMAN (64-404): 1.67e-17: 87.1: 14.74		SC31A_HUMAN (741-1068): 3.97e-10: 66.6: 9.06