HitPredict

Interactor 1: TAF11 (Q15544)
Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28)
Gene: TAF11

Interactor 2: TAF12 (Q16514)
Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15)
Gene: TAF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

The method score is based on:

Property	Details
Experiments	29111974, 33961781, 7729427
Identification Methods	affinity chromatography technology, coimmunoprecipitation, molecular sieving, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	TAFII28~TFIID_20kDa
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006366 - transcription by RNA polymerase II and 6 others more... GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0017025 - TBP-class protein binding GO:0042789 - mRNA transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	211
Hs

1	161

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024