Interactor 1: TERF2 (Q15554)
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
Gene: TERF2
Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23994477, 24012755, 25533185, 31495888, 32398829, 37071664, 19596235, 19596236 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000781 - chromosome, telomeric region GO:0005654 - nucleoplasm GO:0032206 - positive regulation of telomere maintenance GO:0061820 - telomeric D-loop disassembly GO:1904357 - negative regulation of telomere maintenance via telomere lengthening |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
