Interactor 1: TERF2 (Q15554)
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
Gene: TERF2

Interactor 2: TE2IP (Q9NYB0)
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1)
Gene: TERF2IP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 26450775, 23086976, 27214791, 29126443, 15100233, 24981860, 10888888, 35271311, 21829167, 21217703, 21044950, 23307557, 26496610, 28082411, 10850490, 34079125, 34187905, 15383534, 15316005, 19164295 and 3 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, x-ray crystallography, molecular sieving, isothermal titration calorimetry, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rap1_C~TERF2_RBM
Common GO terms GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000783 - nuclear telomere cap complex
GO:0001673 - male germ cell nucleus
GO:0005634 - nucleus
and 10 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 542
Hs

1 399
+ Hs
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024