Interactor 1: MARE2 (Q15555)
Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2)
Gene: MAPRE2

Interactor 2: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 25416956, 30217970, 26186194, 28514442, 27173435, 32296183, 34079125, 33961781, 35271311, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, validated two hybrid, tandem affinity purification, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, EB1~EB1
Common GO terms GO:0005815 - microtubule organizing center
GO:0005881 - cytoplasmic microtubule
GO:0005925 - focal adhesion
GO:0019901 - protein kinase binding
GO:0031110 - regulation of microtubule polymerization or depolymerization
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 327
Hs

1 268
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024