HitPredict

Interactor 1: TGIF1 (Q15583)
Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1)
Gene: TGIF1

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.620

The method score is based on:

Property Details
Experiments 10199400, 11371641
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005654 - nucleoplasm
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 401
Hs

1 467
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Dm
+ Dm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024