HitPredict

Interactor 1: TGIF1 (Q15583)
Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1)
Gene: TGIF1

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	11682623
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 401 Hs			1 1273
+	Hs
		773202 PBX3_HUMAN (112-360): 6.33e-46: 165: 16.73		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1216208 TF2LX_HUMAN (119-398): 7.44e-43: 151: 30.53		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302438 TGIF2_HUMAN (163-398): 3.16e-42: 150: 50.21		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1222733 MKX_HUMAN (145-376): 5.35e-39: 144: 22.03		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		110654 Q96AL5_HUMAN (112-360): 9.67e-40: 147: 15.44		H3BQL7_HUMAN (1-123): 9.36e-47: 166: 100.00
+	At
		1227626 BLH4_ARATH (88-343): 1.63e-44: 164: 21.30		Q8LCT6_ARATH (114-204): 3.2e-28: 113: 30.77
+	Hs
		257749 PBX1_HUMAN (112-360): 1.6e-45: 164: 15.94		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257805 TF2LX_HUMAN (119-398): 7.44e-43: 151: 30.53		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15