Interactor 1: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Interactor 2: NHRF3 (Q5T2W1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3)
Gene: PDZK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 14531806
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EBP50_C~PDZ, PDZ~PDZ
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0043495 - protein-membrane adaptor activity
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 337
Hs

1 519
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Last updated: 15 Jul 2024