HitPredict

Interactor 1: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Interactor 2: RHGBA (Q6P4F7)
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)
Gene: ARHGAP11A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32203420, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 337 Hs			1 1023
+	Hs
		1075409 NHRF2_HUMAN (1-337): 6.02e-79: 246: 100.00		RHG44_HUMAN (4-592): 3.63e-83: 289: 17.63
+	Hs
		1075417 NHRF2_HUMAN (1-337): 6.02e-79: 246: 100.00		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		153929 NHRF1_HUMAN (2-337): 3.61e-70: 224: 48.87		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		856141 NHRF2_HUMAN (1-337): 6.02e-79: 246: 100.00		CHIO_HUMAN (19-239): 5.59e-67: 234: 20.51
+	Hs
		67911 PDZ1P_HUMAN (4-131): 1.03e-19: 91.2: 33.59		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		253399 MAGI1_HUMAN (2-204): 1.44e-16: 83.1: 21.95		SRGP2_HUMAN (57-638): 1.38e-71: 260: 18.30
+	Mm
		1143388 DLG4_MOUSE (106-233): 1.85e-14: 76.2: 21.48		RHG32_MOUSE (3-641): 1.08e-71: 263: 15.37
+	Hs
		1148378 INADL_HUMAN (3-129): 2.49e-13: 73: 21.81		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		1020174 PTN13_HUMAN (89-239): 2.59e-11: 66.9: 21.05		RHG29_HUMAN (18-647): 6.28e-72: 262: 17.12
+	Hs
		253346 PTN13_HUMAN (89-239): 2.59e-11: 66.9: 21.05		SRGP2_HUMAN (57-638): 1.38e-71: 260: 18.30
+	Hs
		655344 DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31		P85A_HUMAN (50-555): 1.39e-70: 251: 15.92
+	Hs
		1132905 NHRF3_HUMAN (148-263): 7.43e-11: 65: 28.45		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		1148381 DLG3_HUMAN (89-220): 8.62e-10: 61.9: 17.99		RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76
+	Hs
		1119965 LIN7C_HUMAN (9-87): 8.5e-09: 56.6: 40.74		RHG29_HUMAN (18-647): 6.28e-72: 262: 17.12
+	Hs
		1246416 INADL_HUMAN (3-129): 2.49e-13: 73: 21.81		HMHA1_HUMAN (18-404): 1.99e-66: 245: 18.27
+	Hs
		129286 DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31		P85B_HUMAN (48-555): 1.92e-65: 237: 16.93
+	Hs
		63080 SNX27_HUMAN (149-228): 1.89e-09: 60.8: 38.71		RHG42_HUMAN (33-450): 1.81e-63: 234: 17.75
+	Hs
		1271026 DLG3_HUMAN (89-220): 8.62e-10: 61.9: 17.99		RGAP1_HUMAN (20-320): 2.86e-57: 211: 21.81
+	Hs
		1300700 MAGI1_HUMAN (2-204): 1.44e-16: 83.1: 21.95		STA13_HUMAN (84-205): 3.11e-10: 66.6: 36.80