HitPredict

Interactor 1: DIXC1 (Q155Q3)
Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)
Gene: DIXDC1

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 683 Hs			1 649
+	Hs
		521556 ACTN1_HUMAN (13-574): 9.47e-137: 425: 15.83		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		211589 ACTN4_HUMAN (16-599): 1.42e-125: 396: 14.63		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		963341 SPTB2_HUMAN (9-577): 3.82e-97: 330: 17.21		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Dm
		574825 ACTN_DROME (13-561): 3.6e-124: 393: 14.55		TITIN_DROME (173-542): 1.72e-27: 121: 13.80
+	Hs
		521586 ACTN1_HUMAN (13-574): 9.47e-137: 425: 15.83		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Hs
		725681 ACTN2_HUMAN (13-578): 1.19e-136: 425: 16.07		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Hs
		598142 FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		261272 FLNB_HUMAN (12-167): 1.24e-44: 174: 24.71		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		974086 DYST_HUMAN (6-142): 3.04e-44: 174: 24.82		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		993278 ACTN3_HUMAN (13-577): 9.22e-129: 404: 14.94		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Hs
		211629 ACTN4_HUMAN (16-599): 1.42e-125: 396: 14.63		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Hs
		963358 SPTB2_HUMAN (9-577): 3.82e-97: 330: 17.21		MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11
+	Hs
		598171 FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71		NIPBL_HUMAN (124-505): 2.57e-30: 130: 11.06
+	Dm
		1337379 FLNA_DROME (12-167): 3.83e-46: 179: 23.73		TITIN_DROME (173-542): 1.72e-27: 121: 13.80
+	Hs
		598253 FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Xl
		844438 DVL2_XENLA (601-683): 1.69e-35: 145: 40.96		Q6DDZ8_XENLA (202-631): 1.69e-19: 95.7: 15.24
+	Hs
		151109 DVL2_HUMAN (601-680): 8.09e-38: 152: 41.25		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55