HitPredict

Interactor 1: G5EFG1 (G5EFG1)
PDZ and LIM domain protein Zasp
Gene: alp-1

Interactor 2: H2L2C8 (H2L2C8)
Alpha-actinin, sarcomeric
Gene: atn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	19123269, 23549480, 14704431
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030018 - Z disc GO:0030036 - actin cytoskeleton organization GO:0055120 - striated muscle dense body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 684 Ce			1 823
+	Ce
		104996 G5EC72_CAEEL (1-397): 1.9e-72: 242: 100.00		Q23158_CAEEL (1-823): 0: 553: 95.41
+	Dm
		54833 ZASP_DROME (273-684): 9.4e-60: 220: 31.80		ACTN_DROME (1-823): 0: 566: 63.00
+	Ce
		107755 G5EFL5_CAEEL (297-622): 5.66e-25: 113: 14.33		Q23158_CAEEL (1-823): 0: 553: 95.41
+	Hs
		117270 PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79		ACTN3_HUMAN (1-823): 0: 548: 60.85
+	Ce
		103987 G5EC72_CAEEL (1-397): 1.9e-72: 242: 100.00		G5EBH3_CAEEL (1-512): 2.88e-91: 318: 37.09
+	Ce
		104744 G5EFG1_CAEEL (1-684): 1.39e-152: 459: 100.00		G5EC35_CAEEL (192-791): 3.35e-09: 63.1: 9.67
+	Mm
		1186636 PDLI5_MOUSE (15-684): 1.31e-89: 293: 22.11		ACTN1_MOUSE (82-823): 2.33e-12: 72.7: 12.89
+	Mm
		1337461 LDB3_MOUSE (15-684): 8.1e-83: 278: 22.04		ACTN2_MOUSE (82-823): 1.88e-16: 86.2: 12.45
+	Hs
		254385 LDB3_HUMAN (15-684): 8.88e-80: 270: 22.19		ACTN2_HUMAN (82-823): 2.15e-16: 85.8: 12.45
+	Hs
		254383 LDB3_HUMAN (15-684): 8.88e-80: 270: 22.19		ACTN1_HUMAN (82-823): 7.22e-13: 74.6: 12.64
+	Hs
		1045539 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		SPTN1_HUMAN (218-688): 5.92e-20: 97.9: 13.29
+	Hs
		725704 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		ACTN2_HUMAN (82-823): 2.15e-16: 85.8: 12.45
+	Hs
		963432 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		SPTB2_HUMAN (183-767): 2.83e-14: 79.7: 13.85
+	Hs
		211672 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		ACTN4_HUMAN (82-802): 5.6e-13: 75: 13.23
+	Hs
		521623 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		ACTN1_HUMAN (82-823): 7.22e-13: 74.6: 12.64
+	Hs
		506846 PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95		SPTB1_HUMAN (158-815): 1.21e-09: 64.2: 10.86
+	Hs
		117257 PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79		ACTN2_HUMAN (82-823): 2.15e-16: 85.8: 12.45
+	Hs
		117234 PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79		ACTN4_HUMAN (82-802): 5.6e-13: 75: 13.23
+	Hs
		117245 PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79		ACTN1_HUMAN (82-823): 7.22e-13: 74.6: 12.64
+	Hs
		521502 PDLI4_HUMAN (567-622): 5.16e-10: 63.4: 26.79		ACTN1_HUMAN (82-823): 7.22e-13: 74.6: 12.64